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Q-Sense D300

The D300 enables reliable QCM-D measurements.

Since 1999, Q-Sense D300 has been succesfully used in several different research applications as can be seen in the many publications in which the instrument is used. The D300 has a straight forward design that enables accurate individual sample analysis.




System overview Q-Sense D300

The D300 consists of the following items. In addition installation and education is included.

Measurement Chamber QAFC 302
QAFC 302 is developed for batch or flow measurements. It is temperature controlled by using a Peltier element. A central flow guarantees a good flow profile. The sensor crystals are easily mounted in the chamber.
Electronics Unit QE 301
The Electronics Unit is the core of the system. It enables high sensitivity, multi-frequency and temperature-controlled measurements. The Electronics Unit is the link between the Measurement Chamber and the PC.
Software QSoft 301 and QTools 2.0 (new)
QSoft 301 is used to acquire data. The responses of the two parameters, f and D, are plotted on the PC-screen in real time. QTools is used for data analysis, for example to create different plots or to conduct mathematical modelling of measurement results.
Sensor Crystals
We use 5 MHz AT-cut, optically polished quartz crystals. Q-Sense offers sensor crystals with a variety of surface, for example Polystyrene, Stainless steel and SiO2.


Specifications

Measurement chambers
Axial flow chamber (QAFC 302)
Constant flow rate between 0 and 0.2 ml/min without external temperature stabilisation.
Constant flow rate maximum 2 ml/min with external temperature stabilisation.
Measurement volume ~ 80 µl
Exchange volume optimum ~ 2 ml minimum ~ 0.8 ml
Working temperature 18 to 40°C, stability ± 0.02 K
Window chamber (QWIC 301)
Measurement volume ~ 0.40 ml
Working distance to microscope 4 - 8 mm
Minimum bench-to-lens distance 28 mm
Working temperature 18 to 40°C, stability ± 0.03 K
Frequency and Dissipation Characteristics
Frequency range 1 - 42 MHz
Frequency resolution 0.01 Hz
Mass resolution, using Sauerbrey  1.8 pg/mm2 (0.18 ng/cm2)
Dissipation resolution 1 x 10-9
Active sensor area 7mm2
Conditions: 1 datapoint / 5 seconds, 20-37 °C, water
Smallest detectable change in f* 0.05 Hz corresp. to 0.9 ng/cm2 (9 pg/mm2)
Smallest detectable change in D* 0.04 x 10-6
Conditions: 4 datapoints / second, 20-37 °C, water
Smallest detectable change in f* 0.2 Hz corresp. to 3.5 ng/cm2 (35 pg/mm2)
Smallest detectable change in D* 0.1 x 10-6
* As comparison, binding of Myoglobin, a small globular protein (Mw 17.8 kD) that forms a rigid monolayer, gives a frequency response of 10 Hz and a Dissipation of ~0.2x10-6. Mefp-1, an elongated protein (Mw 120 kD) forming a soft structure, has a corresponding dissipation of ~12x10-6 and a frequency response of 60 Hz.
Max load ~ 0.1 mg/cm2
Max film thickness ~ 10 µm (depending on the viscoelastic properties of the material)
Software
QSoft 301
Operating system Windows 98/ME/NT/2000/XP
Interface Parallel port o
Normal rate, low noise ~ 4 data points per second
Maximum output rate ~ 15 data points per second
QTools
Viscoelastic models incorporated Voight/Maxwell 
Picture formats Bitmap, Metafile, Enhanced Metafile, JPEG
Input data Frequency and dissipation from min. 2 frequencies
Output data Modeled values of density, shear modulus, viscosity and thickness

Dimensions
Measure Electronics unit Axial Flow Chamber Window Chamber
Height (cm) 28 12 5
Width (cm) 24 12 11
Depth (cm) 42 11 11
Weight (kg) 8.2 1.4 0.3



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Dr. Agnieszka Kowalczyk
Your contact in Poland
Phone: +48 322482048
Fax: +48 322482048
kowalczyk@lot-oriel.com



Dr. Jürgen Schlütter
Phone: +49 6151 880644
Fax: +49 6151 880689
schluetter@lot-oriel.de

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